Ordering Recommendation

May aid in the diagnosis of rapidly progressive vision loss and suspected paraneoplastic autoimmune retinopathy or optic neuropathy.

New York DOH Approval Status

This test is New York state approved.

Specimen Required

Patient Preparation
Collect

Serum separator tube.

Specimen Preparation

Separate serum from cells ASAP or within 2 hours of collection. Transfer 1 mL serum to an ARUP standard transport tube. (Min: 0.30 mL)

Storage/Transport Temperature

Refrigerated.

Unacceptable Conditions

Plasma. Contaminated, heat-inactivated, hemolyzed, or lipemic specimens.

Remarks
Stability

After separation from cells: Ambient: 48 hours; Refrigerated: 2 weeks; Frozen: 1 month

Methodology

Qualitative Immunoblot/Semi-Quantitative Cell-Based Indirect Fluorescent Antibody

Performed

Varies

Reported

1-8 days

Reference Interval

Test Number
Components
Reference Interval
  CV2 Ab IgG CBA-IFA Screen, Serum Less than 1:100
  Recoverin Ab, IgG by Immunoblot, Serum Negative

Interpretive Data

Refer to report

Compliance Category

Laboratory Developed Test (LDT)

Note

If CV2 Antibody IgG Screen by IFA is positive, then CV2 Antibody IgG Titer by IFA will be added. Additional charges apply.

Hotline History

N/A

CPT Codes

84182, 86255; if reflexed, add 86256

Components

Component Test Code* Component Chart Name LOINC
2013959 CV2 Ab IgG CBA-IFA Screen, Serum 72504-4
3016805 Recoverin Ab, IgG by Immunoblot, Serum 83003-4
* Component test codes cannot be used to order tests. The information provided here is not sufficient for interface builds; for a complete test mix, please click the sidebar link to access the Interface Map.

Aliases

  • Cancer-associated retinopathy
  • CAR
  • CRMP5
  • CV2
  • Opthalmitis
  • Optic neuropathy
  • Recoverin
  • Vision loss
Autoimmune Vision Loss Panel, Serum